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Enlist® herbicides offer both effective weed control plus near-zero volatility. Here’s what you need to know for on-target applications this season.

March 1, 2024

4 Min Read
4 Tips for On-target Herbicide Applications
Submitted by Corteva Agriscience

Herbicide drift is something many growers dread. Off-target applications can reduce weed control efficacy and damage neighboring crops, creating the potential for fines. Luckily, these issues are avoidable with the right trait technology and proper steps for precision applications.

Advantages of Enlist® Herbicides

The Enlist® weed control system provides effective weed control and herbicides with near-zero volatility. Enlist E3® soybeans and Enlist® cotton  varieties offer tolerances to 2,4-D choline, glufosinate and glyphosate. Enlist® corn offers the same tolerances plus tolerance to FOP herbicides. Enlist One® herbicide  and Enlist Duo® herbicide  are the only 2,4-D herbicides approved for use with crops with the Enlist® trait.

Texas-based Enlist® field specialist Ben Benton explains what makes Enlist® herbicides unique: “Both contain the active ingredient 2,4-D choline with Colex-D technology, which has a significant advantage over traditional 2,4-D formulations. When used according to label, Enlist herbicides stay where sprayed for dependable weed control.”

Here’s Enlist® herbicides differ from 2,4-D ester and amine:

  • 2,4-D choline is 96% less volatile than 2,4-D ester.

  • 2,4-D choline is 88% less volatile than 2,4-D amine.

“Not only is using generic 2,4-D off label, it’s foolish,” says Benton. “For example, cotton without the Enlist trait is highly sensitive to 2,4-D, and older forms of the ingredient are very prone to volatility. It doesn’t take much 2,4-D to cause symptomology on susceptible cotton. With generics, the symptomology can show up far from the source. With Enlist® herbicides, your risk for volatility is greatly diminished.”

Benton says, Enlist herbicides also provide several advantages over dicamba, including:

  • No calendar cutoff dates

  • Greater tank-mix flexibility

  • No drift/volatility-reducing adjuvants required

Benton says dicamba drift has caused significant yield losses on vulnerable crops across the South. However, he says, when used correctly, the Enlist® system can prevent these issues while providing effective weed control.

Tips for On-target Applications

While Enlist herbicides do offer near-zero volatility, Benton says, it’s still essential to follow best practices for on-target applications. Here are four of his tips for success:

  1. Confirm field placement. “Proper field placement is paramount to avoid harming any nearby susceptible crops, such as cotton without the Enlist trait, grapes or tomatoes,” Benton says. “I recommend talking with neighbors about what’s planted in surrounding fields and working together to prevent crop damage.”

  2. Set up sprayer correctly. “Next, get your sprayer properly set up,” Benton says. “Make sure you have qualified nozzles and pressure combinations, and adjust for the correct spray rate, spray volume and boom height.”

  3. Watch the wind. “To prevent drift, target applications of Enlist One or Enlist Duo herbicide when the wind speed is greater than 3 mph, but less than 10 mph. Some states have different wind speed regulations though, so check your state requirements before applying,” Benton says. “And remember: Only spray when the wind is blowing away from susceptible crops.”

  4. Do not apply during temperature inversions.Temperature inversions can create conditions for off-target herbicide movement,” Benton says. “Inversions are most likely to happen between dusk and dawn.”

Benton says these best practices are a good place to start, but he advises reading the application guide,  as well as the Enlist One herbicide label and/or Enlist Duo herbicide label to ensure precision application.

“The Enlist system gives growers the flexibility to strive for the best weed control possible. Using Enlist herbicides as part of a multipass program approach is key to the success and longevity of this superior technology,” Benton says. “Another key is growers working as a community to ensure safe herbicide applications.”

Find more resources for precision applications on the Tech Topics – On-target Applications page at

™ ® Trademarks of Corteva Agriscience and its affiliated companies. The transgenic soybean event in Enlist E3® soybeans is jointly developed and owned by Corteva Agriscience and M.S. Technologies L.L.C. Enlist Duo® and Enlist One® herbicides are not registered for sale or use in all states or counties. Contact your state pesticide regulatory agency to determine if a product is registered for sale or use in your area. Enlist Duo and Enlist One herbicides are the only 2,4-D products authorized for use with Enlist® crops. Consult Enlist® herbicide labels for weed species controlled. Always read and follow label directions. ©2024 Corteva. 019052  BR (02/24)  CAAG4NLST067

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